Introduction

Uses of Twindopa 275

Parkinson's disease

Side effects of Twindopa 275

Nausea
Vomiting
Dryness in mouth
Constipation
Dizziness
Sleepiness
Headache
Abnormal dreams
Anxiety
Insomnia (difficulty in sleeping)
Abnormality of voluntary movements
Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Twindopa 275

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Twindopa 275 is to be taken empty stomach. \nAvoid Twindopa 275 with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Twindopa 275 works

Twindopa 275 is a combination of two medicines: Levodopa and Carbidopa which treats Parkinsonism. Levodopa is a dopamine precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents breakdown of levodopa allowing it to enter the brain and increase dopamine levels.

Quick Tips

You have been prescribed Twindopa 275 to treat your symptoms of Parkinson's disease.
It can be taken with or without food or as directed by your doctor.
Reduce/avoid a high-protein diet (e.g. meat, poultry, and dairy products) while you are taking the medicine as it can reduce the amount of medication absorbed by your body.
Be cautious while driving or doing anything that requires concentration as Twindopa 275 can make you very sleepy.
When you start the medication, get out of bed slowly, as the medication may cause dizziness, lightheadedness or fainting.
Do not stop taking the medication without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating, and confusion.
Talk to your doctor in case you develop hallucinations or other changes in your behavior.

Safety Advice

UNSAFE – Alcohol: It is unsafe to consume alcohol with Twindopa 275.
CONSULT YOUR DOCTOR – Pregnancy: Twindopa 275 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED – Breastfeeding: Twindopa 275 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.\nPartial to complete suppression of lactation was seen in mothers on the treatment with Twindopa 275, but when the treatment was stopped, lactation returned to normal levels.
UNSAFE – Driving: Twindopa 275 may cause side effects which could affect your ability to drive.\nAs Twindopa 275 may cause dizziness, drowsiness, double vision, which may affect your ability to react which may affect your ability to drive.
SAFE IF PRESCRIBED – Kidney: Twindopa 275 is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Twindopa 275 may not be needed in these patients. Please consult your doctor.
CAUTION – Liver: Twindopa 275 should be used with caution in patients with liver disease. Dose adjustment of Twindopa 275 may be needed. Please consult your doctor.