Indications

This is intended as a supplement for intravenous nutrition in order to meet the daily requirements of the water-soluble vitamins of dehydrated patients.

Composition

Each vial contains:
. Vitamin B1 (as Thiamine Nitrate): 2.5 mg
- Vitamin B2 (as Riboflavin Sodium Phosphate): 3.6 mg
. Nicotinamide: 40 mg
Vitamin B6 (as Pyridoxine Hydrochloride): 4 mg
. Pantothenic Acid (as Dexpanthenol): 15 mg
. Ascorbic Acid (as Sodium Ascorbate): 100 mg
. Biotin: 0.06 mg
. Folic Acid: 0.4 mg
. Vitamin B12 (as Cyanocobalamin): 0.005 mg

Pharmacology

This is a sterile, lyophilized powder of water-soluble vitamins for infusion. It contains balanced amount of all the important water soluble vitamins which act as coenzymes of vital enzymes associated
with crucial physiological processes, energy metabolism, cell growth and replenishment especially in brain and nerve cells. Vitamin C acts as an antioxidant and helps in collagen formation. Intravenous
administration of this combination gives prompt action.

Dosage & Administration

Adults and children weighing 10 kg or more: 1 vial (10 ml) daily.
Children weighing less than 10 kg: should be given 1 ml of the dissolved mixture per kg body weight/day.

The contents of one vial are dissolved by the aseptic addition of 10 ml of one of the following:
. Water for injection
. Fat emulsion 10%
Glucose solution for infusion (5% to 60%)
. Normal saline (0.9% Sodium Chloride)
This IV preparataion may be added to parenteral nutrition admixtures containing carbohydrates, lipids, amino acids, electrolytes, and trace elements provided that compatibility and stability have been
confirmed.

Interaction

Vitamin B6 can reduce the effect of Levodopa. Folic Acid may lower the serum concentration of Phenytoin.

Contraindications

Known hypersensitivity to any of the components, e.g. Thiamine.

Side Effects

Allergic reactions may occur in patients hypersensitive to any component of the preparation, e.g. Thiamine.

Pregnancy & Lactation

Animal reproduction studies or clinical investigations during pregnancy have not been carried out with this preparation. However, there are published reports on safe administration of water-soluble
vitamins in this patient group.