Indications

Glutathione is considered the body’s “master antioxidant”, playing a vital role in:

Free radical protection: Neutralizes reactive oxygen species (ROS) to prevent cellular damage.
Detoxification: Helps remove toxins, pollutants, and drug metabolites.
Immune support: Maintains healthy immune cell function.
Age-related decline: Levels decrease with aging, linked to conditions such as cancer, HIV/AIDS, type 2 diabetes, hepatitis, and Parkinson’s disease.
Lifestyle impact: Poor diet, stress, chemical exposure, and extreme exercise can deplete glutathione reserves.

Pharmacology

Glutathione influences three key areas of immune health:

Gastrointestinal integrity: Protects intestinal mucosa, reduces epithelial permeability, and prevents bacterial translocation.
Mitochondrial protection: Shields mitochondria during ATP production, ensuring efficient energy metabolism.
Immune cell regulation: Maintains T-lymphocyte and NK cell activity; supplementation shown to double NK cell cytotoxicity in clinical trials.

Clinical studies (European Journal of Nutrition, 2015) show oral supplementation at 250 mg to 1,000 mg daily for 6 months increases glutathione levels in blood, erythrocytes, and buccal cells.
Setria glutathione demonstrated significant uptake and immune benefits.