Indications

Combicid cream is indicated in the treatment of-
. Mixed and complicated Fungal, Protozoal & Bacterial infections,
. Mild to moderate vaginitis,
Candidiasis and trichomoniasis,
. Pruritus vulvae,
. Dermatitis,
. Eczema,
. Genito-urinary infections.

Composition

Each gram cream contains-
. Clobetasol Propionate USP 0.50 mg
. Ofloxacin USP 7.50 mg
. Ornidazole INN 20 mg
· Terbinafine Hydrochloride BP 10 mg

Pharmacology

This cream is a combination cream which exhibits anti-bacterial, anti-fungal, anti-protozoal & anti-inflammatory actions. Ofloxacin is a broad-spectrum antibiotic that acts against many gram-positive
& gram-negative bacteria. Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. Terbinafine is an Allylamine antifungal that inhibits
biosynthesis of Ergosterol (an essential components if fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. Clobetasol is a potent corticosteroid which exhibits
anti-inflammatory, anti-pruritic and vasoconstrictive properties.

Dosage & Administration

Apply by gently rubbing onto the affected area twice daily.

Interaction

No hazardous interactions have been reported.

Contraindications

Contraindicated in patients hypersensitive to any of the components of the formulation.

Side Effects

Burning, itching, irritation, dry skin

Pregnancy & Lactation

The safe use of this preparation during pregnancy & lactation has not been established.

Precautions & Warnings

Do not shallow. For external use only