Introduction

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Uses of Diplin M 500

Type 2 diabetes mellitus

Side effects of Diplin M 500

Diarrhea
Nausea
Vomiting
Upset stomach
Headache
Nasal congestion (stuffy nose)
Sore throat
Respiratory tract infection
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Diplin M 500

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diplin M 500 is to be taken with food.

How Diplin M 500 works

Diplin M 500 is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Linagliptin is a DPP-4 inhibitor which works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

What if you forget to take Diplin M 500?

If you miss a dose of Diplin M 500, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Trajenta Duo 2.5mg/500mg Tablet should be taken with food to lower the chances of having an upset stomach.
Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anaesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Trajenta Duo 2.5mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Safety Advice

UNSAFE – Alcohol: It is unsafe to consume alcohol with Diplin M 500.
SAFE IF PRESCRIBED – Pregnancy: Diplin M 500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED – Breastfeeding: Diplin M 500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CAUTION – Driving: Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION – Kidney: Diplin M 500 should be used with caution in patients with kidney disease. Dose adjustment of Diplin M 500 may be needed. Please consult your doctor.\nUse of Diplin M 500 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
CAUTION – Liver: Diplin M 500 should be used with caution in patients with liver disease. Dose adjustment of Diplin M 500 may be needed. Please consult your doctor.\nDiplin M 500 is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.