Indications

Cystnil tablet is indicated for the treatment and prevention of-
. Polycystic ovary syndrome (PCOS) associated symptoms such as menstrual irregularity, anovulation, hirsutism, acanthosis nigricans, aene, obesity and PCOS associated infertility
. Gestational diabetes mellitus
. Ovarian hyperstimulation syndrome
Intertility
Miscarnage

Pharmacology

D-chiro-inositol is a naturally occurring inositol isomer extracted by a patented process from Carob (Ceratonia siliqua) pod native to Southem Europe. The perfect combination of D-chiro-inositol and Myo-
inositol with a specifie ratio may help to correct the hormonal imbalance and menstrual cycle to achieve ovulation. This combination signifcantly decreases the level of prolactin hormone, testosterone hormone,
luteinizing hormone and also balances the ratio of follicle-stimulating hormone and luteinizing hormone. It increases insulin sensitivity, estrogen hormone level and reduces oxidative stress within the ovarian
tollicles. It helps in follicular development, improves egg quality, and restores ovulation in women to enhance the chances of pregnancy. It helps to prevent the onset of gestational diabetes mellitus. It also
reduces symptoms associated with PCOS and improves fertility in women with PCOS.

Dosage & Administration

Orally 2 tablets daily or as advised by the physician. Duration of treatment should be at least 3 months or as advised by the physician.

Interaction

Concurrent use with digodn may result in increased digoxin toxicity. Concomitant use of D-chiro-inositol and Myo-inositol may potentiate the effect of antidiabetie drugs.

Contraindications

Contraindicated in patients with known hypersensitivity to D-chiro-inositol and Myo-inositoL

Side Effects

Benerally well tolerated in the recommended dose. Occasionally may occur nausea, diarrhea and flatulence.

Pregnancy & Lactation

Several human studies have been conducted in pregnant women with D-chiro-inositol and Myo-inositol combination that show no clinically relevant adverse effects. There are no published clinical data on the
safety of D-chiro-inositol and Myo-inositol during lactation.

Precautions & Warnings

Limited data is available regarding the usage in patients with liver & hepatic impairment. Patient should consult with doctor if the patient has a liver or hepatie impairment or any concerns regarding this.

Therapeutic Class

Herbal and Nutraceuticals

Storage Conditions
Store below 30" C temperature & dry place, protected from light. Keep all medicines out of reach of children.