Introduction

Uses of Secrin M 2/500 XR

Type 2 diabetes mellitus

Side effects of Secrin M 2/500 XR

Hypoglycemia (low blood glucose level)
Taste change
Nausea
Diarrhea
Stomach pain
Headache
Upper respiratory tract infection

How to use Secrin M 2/500 XR

Use it as advised by your doctor or check the label for directions before use. Secrin M 2/500 XR is to be taken with food.

How Secrin M 2/500 XR works

Secrin M 2/500 XR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Quick Tips

Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Gemer 1 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety Advice

UNSAFE – Alcohol: It is unsafe to consume alcohol with Secrin M 2/500 XR.
CONSULT YOUR DOCTOR – Pregnancy: Secrin M 2/500 XR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED – Breastfeeding: Secrin M 2/500 XR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CAUTION – Driving: Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION – Kidney: Secrin M 2/500 XR should be used with caution in patients with kidney disease. Dose adjustment of Secrin M 2/500 XR may be needed. Please consult your doctor.\nUse of Secrin M 2/500 XR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
CAUTION – Liver: Secrin M 2/500 XR should be used with caution in patients with liver disease. Dose adjustment of Secrin M 2/500 XR may be needed. Please consult your doctor.\nSecrin M 2/500 XR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.