Introduction

Uses of Siglimet 50/500

Type 2 diabetes mellitus

Side effects of Siglimet 50/500

Diarrhea
Nausea
Vomiting
Upset stomach
Headache
Nasal congestion (stuffy nose)
Sore throat
Respiratory tract infection
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Siglimet 50/500

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siglimet 50/500 is to be taken with food.

How Siglimet 50/500 works

Siglimet 50/500 is a combination of two antidiabetic medicines: Sitagliptin and Metformin. They help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Together, they provide better control of blood sugar.

Quick Tips

Take it with food to lower your chance of having an upset stomach.
Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Janumet XR CP Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Safety Advice

UNSAFE – Alcohol: It is unsafe to consume alcohol with Siglimet 50/500.
SAFE IF PRESCRIBED – Pregnancy: Siglimet 50/500 is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED – Breastfeeding: Siglimet 50/500 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CAUTION – Driving: Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
CAUTION – Kidney: Siglimet 50/500 should be used with caution in patients with kidney disease. Dose adjustment of Siglimet 50/500 may be needed. Please consult your doctor.\nUse of Siglimet 50/500 is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
SAFE IF PRESCRIBED – Liver: Siglimet 50/500 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Siglimet 50/500 may not be needed in these patients. Please consult your doctor.