Indication

Hyperphosphatemia

Administration

Should be taken with food.

Contraindication

Patients with hypercalcaemia.

Mode of Action

Sequesters phosphate in the intestine by forming insoluble phosphates that are excreted faecally, thus reducing serum phosphate conc & secondary hyperparathyroidism.

Precaution

Patients undergoing chronic hemodialysis. Renal impairment, diseases associated with hypercalcaemia such as sarcoidosis & some malignancies. Avoid in patients with calcium renal calculi or a history of renal calculi.\r\n\r\nMaintenance of normal serum calcium levels is important for maternal and fetal well being; hypercalcemia during pregnancy may increase risk for maternal and neonatal complications(eg, stillbirth, preterm delivery, neonatal hypocalcemia and hypoparathyroidism);calcium acetate treatment, as recommended, is not expected to harm a fetus if maternal calcium levels are properly monitored during and following treatment\r\n\r\nLactation: unknown

Side Effect

Arrhythmias,Hypomagnesemia,Hypophosphatemia,Hypotension,Nausea,Pruritus (rare),Weakness\r\nHypercalcemia,Anorexia,Coma,Confusion,Delirium,Headache,Nausea,Vomiting

Pregnancy Category Note

Pregnancy Category: C\r\nMaintenance of normal serum calcium levels is important for maternal and fetal well being; hypercalcemia during pregnancy may increase risk for maternal and neonatal complications(eg, stillbirth, preterm delivery, neonatal hypocalcemia and hypoparathyroidism);calcium acetate treatment, as recommended, is not expected to harm a fetus if maternal calcium levels are properly monitored during and following treatment\r\n\r\nLactation: unknown

Interaction

Tetracycline antibiotics, thiazide diuretics, vit D, corticosteroids, bisphosphonates, fluoride, some fluoroquinolones.