Indications

Emergency contraception to prevent pregnancy after unprotected intercourse.
Should be taken as soon as possible, preferably within 12 hours, and no later than 72 hours (3 days).
Recommended in cases of:
- No contraceptive method used.
- Missed consecutive contraceptive pills.
- Condom failure (broken, slipped, or not used).
- Suspected expulsion of intrauterine device.
- Vaginal diaphragm or contraceptive cap displacement.
- Failure of coitus interruptus or rhythm method.
- Sexual assault (rape).

Composition

Description

Pharmacology

Dosage & Administration

15 mg tablet: Single dose, taken as soon as possible within 72 hours.
0.75 mg tablets: First tablet within 72 hours, second tablet 12 hours later.
Oral administration with water.
If vomiting occurs within 3 hours, another tablet should be taken immediately.
After use, barrier contraception (condom, spermicide, cervical cap) is recommended until next menstrual period.
Continue regular contraceptive pills if already in use.

Interactions

Effectiveness reduced by anticonvulsants (phenobarbital, phenytoin, primidone, carbamazepine), rifampicin, griseofulvin, and other enzyme-inducing drugs.

Contraindications

Hypersensitivity to Levonorgestrel or excipients.
Not indicated in existing pregnancy.
Not recommended in ectopic pregnancy history, salpingitis, or severe digestive disorders affecting absorption.

Side Effects

Pregnancy & Lactation

Not effective if implantation has already occurred.
No evidence of teratogenic effects if pregnancy continues.
Levonorgestrel is secreted in breast milk; breastfeeding should be avoided for several hours after intake.

Precautions & Warnings

For occasional use only; not a substitute for regular contraception.
Menstrual period may occur earlier or later than expected.
Pregnancy test recommended if menstruation is delayed >5 days or abnormal bleeding occurs.
Does not protect against sexually transmitted infections (STIs).
Medical advice recommended for ongoing contraception.

Overdose Effects