Indications Cutin is indicated for hair loss, weak or brittle nails, splitting or soft nails, eczema, and dermatitis.

Pharmacology Biotin, also known as Vitamin H, is an essential vitamin involved in fatty acid synthesis, amino acid catabolism, and gluconeogenesis. It acts as a cofactor in the enzymatic carboxylation of pyruvate and acetyl‑CoA. Biotin supports the growth and differentiation of epidermal cells, which are vital for the formation and renewal of skin, hair, and nails. It functions as a coenzyme for mitochondrial carboxylases in hair roots and improves keratin structure. Biotin deficiency may cause hair loss, dermatitis, and aciduria. It is one of the most commonly prescribed nutritional supplements for hair loss.

Dosage & Administration In adults, the usual dose is 1–3 tablets daily or as advised by the physician. In children, biotin deficiency may occur between 1 week and 2 years of age, presenting with seizures, hypotonia, developmental delay, ataxia, hyperventilation, and coma. In such cases, 5–10 tablets daily, crushed and mixed with water or fruit juice, or as advised by the physician.

Recommended Dietary Allowance Infants require 5–6 mcg per day, children 8–12 mcg per day, adolescents 20–25 mcg per day, adults 30 mcg per day, pregnant women 30 mcg per day, and lactating mothers 35 mcg per day.

Interaction Anticonvulsant drugs may lower plasma biotin levels. Antibiotics can reduce biotin production by intestinal microflora. Excessive consumption of raw egg whites interferes with biotin absorption.

Contraindications Contraindicated in patients with known hypersensitivity to any of the ingredients.

Side Effects Well tolerated at recommended doses. No toxicity has been reported even with oral doses up to 200 mg or intravenous doses up to 20 mg per day.

Pregnancy & Lactation Insufficient clinical data are available for use in pregnant or lactating women; use only under medical supervision.