Indications

Relief of muscle spasm in the intestine, biliary system, bladder, and uterus.
Symptomatic treatment of pain related to functional disorders of the digestive tract and biliary system.
Treatment of spasm and pain in urological and gynecological disorders.

Pharmacology Tiemonium Methylsulphate is a competitive antagonist of acetylcholine and histamine, and strengthens calcium binding with membrane phospholipids and proteins.

Inhibits intracellular contractile proteins of visceral cells.
Results in inhibition of visceral spasm and associated pain.

Dosage & Administration

Tablet/Syrup:
- Adults: 2–6 tablets or 3–9 teaspoonfuls syrup daily in divided doses.
- Children: 3 ml/kg or 0.3 mg/kg body weight daily in divided doses.
Injection: 1 injection three times daily, intravenously or intramuscularly.
Suppository: 20 mg, two or three times daily, rectally.

Interactions

Should not be used with other drugs without physician consultation due to possible drug interactions.

Contraindications

Contraindicated in urinary tract disorders with risk of urine retention.
Contraindicated in patients at risk of angle‑closure glaucoma.

Side Effects

May cause hypotension and tachycardia in certain individuals.

Pregnancy & Lactation

Animal studies show no teratogenic effects.
No deformities reported with normal use.
Insufficient human data; caution advised in nursing mothers.

Precautions & Warnings

Use cautiously in patients with prostate disorders.
Caution in chronic bronchitis, coronary insufficiency, ambient hyperthermia, renal and hepatic insufficiency.
Visual disturbances may impair driving or operating machinery.

Use in Special Populations

Pediatric: Safety and efficacy not established.
Geriatric: Efficacy and safety maintained with increasing age.

Overdose Effects

No data available regarding overdose.

Therapeutic Class Anticholinergics.

Storage Conditions Store in a dry place, away from light and heat. Keep out of reach of children.