Merocla is indicated for infections caused by sensitive bacteria:

Pharyngitis/Tonsillitis: due to Streptococcus pyogenes
Acute Otitis Media: due to Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta‑lactamase producing strains), Streptococcus pyogenes
Acute Maxillary Sinusitis: due to Streptococcus pneumoniae, Haemophilus influenzae
Lower Respiratory Tract Infections (including pneumonia): due to Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus, Streptococcus pyogenes, E. coli
Acute Exacerbation of Chronic Bronchitis / Secondary bacterial infection of acute bronchitis
Uncomplicated Skin & Soft Tissue Infections: due to Staphylococcus aureus, Streptococcus pyogenes
Uncomplicated Urinary Tract Infections: due to E. coli, Klebsiella pneumoniae
Bone & Joint Infections: due to Staphylococcus aureus
Uncomplicated Gonorrhea: due to Neisseria gonorrhoeae
Early Lyme Disease (erythema migrans): due to Borrelia burgdorferi
Septicemia: due to Staphylococcus aureus, Streptococcus pneumoniae, E. coli, Haemophilus influenzae, Klebsiella spp.
Meningitis: due to Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Staphylococcus aureus
Switch therapy: injectable to oral.

Cefuroxime: Second‑generation cephalosporin, bactericidal, inhibits bacterial cell wall synthesis. Active against Gram‑positive and Gram‑negative organisms, including beta‑lactamase producers.
Clavulanic Acid: Beta‑lactamase inhibitor, protects cefuroxime from enzymatic degradation, extending its spectrum against resistant bacteria.

Adults & adolescents (≥15 years):
- Pharyngitis/Tonsillitis: 250 mg twice daily for 5–10 days
- Acute sinusitis: 250 mg twice daily for 10 days
- Acute exacerbation of chronic bronchitis: 250–500 mg twice daily for 10 days
- Secondary infections of acute bronchitis: 250–500 mg twice daily for 5–10 days
- Skin/soft tissue infections: 250–500 mg twice daily for 10 days
- UTI: 250 mg twice daily for 7–10 days
- Gonorrhea: 1000 mg single dose
- Community‑acquired pneumonia: 250–500 mg twice daily for 5–10 days
- MDR Typhoid fever: 500 mg twice daily for 10–14 days
- Early Lyme disease: 500 mg twice daily for 20 days
Pediatric (5 months–12 years):
- Pharyngitis/Tonsillitis: 20 mg/kg/day in 2 doses for 5–10 days
- Acute otitis media: 30 mg/kg/day in 2 doses for 10 days
- Acute sinusitis: 30 mg/kg/day in 2 doses for 10 days
- Impetigo: 30 mg/kg/day in 2 doses for 10 days

Note: May be taken with or without food.