Introduction

Uses of Neostig

Myasthenia gravis
Paralytic ileus
Post-operative urinary retention
Reversal of effect of skeletal muscle relaxant after surgery

Side effects of Neostig

Nausea
Vomiting
Abdominal cramp
Diarrhea

How to use Neostig

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neostig may be taken with or without food, but it is better to take it at a fixed time.

How Neostig works

Neostig is a reversible cholinesterase inhibitor. When taken by mouth it increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

What if you forget to take Neostig?

If you miss a dose of Neostig, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick Tips

Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Safety Advice

UNSAFE – Alcohol: Neostig may cause excessive drowsiness with alcohol.
CONSULT YOUR DOCTOR – Pregnancy: Neostig may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED – Breastfeeding: Neostig is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
CONSULT YOUR DOCTOR – Driving: It is not known whether Neostig alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
CAUTION – Kidney: Neostig should be used with caution in patients with kidney disease. Dose adjustment of Neostig may be needed. Please consult your doctor.\nRegular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
SAFE IF PRESCRIBED – Liver: Neostig is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Neostig may not be needed in these patients. Please consult your doctor.