Indication

Adults: \r\nInjection\r\nOne vial (10 ml) daily. \r\n\r\nOral\r\n1-2 Capsule daily.\r\n

Administration

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.

Adult Dose

The combination of Vitamin B-Complex and Vitamin C is one of the most common supplements used to boost energy, support the nervous system, and strengthen the immune system.

Renal Dose

Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increaase chylomicron triglyceride removal from plasma. Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erthropoiesis, nucleprotein and myelin synthesis, cell reproduction and normal growth; intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of Vitamin B12 from the GI tract. Necessary for normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin.\r\nVitamin C is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.\r\n

Contraindication

Oral\r\nChildren age 11 years and above: \r\n1-2 Capsule daily.\r\n\r\nInjection\r\nChildren age 11 years and above: One vial (10 ml) daily. \r\nChildren below 11 years of age: Children weighing less than 10 kg should be given 1 ml of the dissolved mixture per kg body weight /day.\r\nChildren weighing 10 kg or more should be given 10 ml (one vial) of the dissolved mixture /day.

Precaution

Supplement for intravenous nutrition in order to meet the daily requirements of the water-soluble vitamins in infants, adults and children.

Pregnancy Category Note

The unwanted effects of nutrient solutions are a rise in the body temperature, shivering, chills and nausea and vomiting. Adverse reactions that may be expected based on experience with other water-soluble vitamin compounds administered intravenously include: allergic reactions, including anaphylaxis; dermatological reactions including flushing, erythema and pruritus and CNS reactions including headache, dizziness and agitation etc.

Interaction

Hypersensitivity to any of the ingredients of the preparation.