Indications

Adjunctive treatment and temporary relief of symptoms associated with oral inflammatory conditions.
Ulcerative lesions resulting from trauma.

Pharmacology

Triamcinolone acetonide is a topical corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties.
Mechanism: Induces phospholipase A2 inhibitory proteins (lipocortins), which control biosynthesis of inflammatory mediators (prostaglandins, leukotrienes) by inhibiting release of arachidonic acid.

Apply a small dab (about ¼ inch) directly to the lesion until a thin film develops.
Do not rub in; spreading may cause gritty sensation.
Best applied at bedtime for prolonged contact.
May be applied 2–3 times daily, preferably after meals.
If no improvement within 7 days, further investigation is advised.

Local reactions: burning, itching, irritation, dryness, blistering, peeling, perioral dermatitis, allergic contact dermatitis, maceration, secondary infection, oral mucosa atrophy.

Discontinue if local adverse reactions occur.
Allergic contact sensitization may present as failure to heal.
If mucosal infections are present, use appropriate antifungal/antibacterial agents.
Prolonged use may cause systemic absorption → HPA axis suppression, Cushing’s syndrome, hyperglycemia, glucosuria.
Monitor patients on prolonged therapy.
Pediatric patients: greater susceptibility to HPA suppression and growth interference.
Geriatric patients: no significant differences reported compared to younger adults.